Address the root causes of acne pimples, rosacea, redness and post inflammatory marks and scarring with BIOSKINCLEAR, a natural treatment gel

Natural acne treatment can now be accomplished with a new biological gel that unlike other acne medications, drugs, chemical over the counter products or natural acne solutions does not have any side effects and has several other great benefits for your skin.

BIOSKINCLEAR is made with a natural skin care ingredient that exits in nature to function as a support of the innate immune system of a living being with a skin similar to human skin. This creature never suffers from skin infections, because the fluid substance it creates -"a solution"- contains both antimicrobial peptides and molecules that signal the skin to induce the production of their own antimicrobial peptides.

The same substance has the ability to stimulate the healing of human skin lesions and the process of orderly repair of skin tissues, while it also deeply moisturizes the skin and impairs free radical oxidation generated by the metabolic process of skin regeneration.

Scientific screening of the ingredient shows it contains glycoconjugates which are highly complex acidic sugar molecules (glycans) bound to proteins and trace elements (Zinc, Copper, Calcium and Iron) that work as enzymes and contribute to deactivate free radicals and dissolve abnormal scars and damaged tissues. The glycoproteins also play an important role in enhancing the intricate process of communication among cells, thus helping to heal skin without abnormal scarring. The ingredient also has a fibroblast growth factor activity which stimulates the cells in the basal layer of the skin that give rise to glycosaminoglycans and proteoglycans, the water holding molecules in healthy skin – true moisturizing- and regenerate the connective tissues in the skin matrix, the collagen and elastin that provide skin with elasticity and strenght.

Acne is mostly an inflammatory reaction to lesions caused by sebum outbreaks to cells lining the hair follicles, and/or to similar lesions inflicted by chemicals produced by the proliferation of acne bacteria within blocked pores.

Acne treatment must repair skin lesions and combat inflammation, blocked pores and acne bacteria, and always aim to prevent loss of tissues as in ice icepick or pitted acne scars or abnormal raised or keloid scars.

A big majority of the treatments have been created to either eliminate bacteria with severe chemicals, dry out the skin to eliminate most of the oil produced by your own skin, cleanse pores by partially exfoliating some of the outer layer of your skin using natural or chemical acids, abate sebum generation with dangerous drugs, or a mixture of all of them.

Most Acne & Rosacea Treatment Products Only Attack The Symptoms:

Bacterial Infection with harsh chemical substances that produce irritation, redness, extreme dryness and free radicals that damage healthy cells and trigger premature aging of skin, or antibiotics that have become useless as they induce the development of bacteria resistant to antibiotics, also a problem when more serious health problems need to be taken care of.

Blocked Skin Pores with harsh chemical substances that destroy tissues or release free radicals such as benzoyl peroxide, salicylic, glycolic, lactic or other strong acids that cause peeling and dryness, secondary reactions that can make acne even worse.

Reduction of Sebum Production with artificial treatments or treatment products, or with dangerous Isotretinoin or Vitamin A drugs (Accutane® , Retin-A and other brands) that have caused secondary reactions, and can’t be used by any women that are pregnant or could become pregnant because it causes terrible birth deformities. We also have to mention the undesired effects on skin: dry skin, nose bleed, irritation of eyelids and eyes, skin itching, skin fragility, chapped lips, awfal scaling and peeling, among many other.

Skin Inflammation with anti-inflammatory cures such as prescription systemic corticosteroids and steroid injections that also have immunosuppressant reactions that may be contraindicated, or have undesired secondary reactions: our skin can become extremely sensitive, tearing and bruising in a very easy way, making it prone to stretch marks. Or treatment products with non-steroid drugs such as ibuprofen which often causes unsatisfactory gastrointestinal secondary reactions including diarrhea, bloating, heartburn, upset stomach (dyspepsia) and ulcers.

BIOSKINCLEAR treats the root causes of acne and rosacea inflammation and not just the symptoms.

A root cause is an initiating cause of a causal chain which leads to an outcome or effect of interest. Normally, root cause is used to describe the depth in the causal chain where an intervention could easily be used to change performance and prevent an unwanted consequence.

BIOSKINCLEAR is a natural breakthrough treatment product that works because it addresses the main cause of these two inflammatory skin problems with a biological treatment gathered from a unique source and not just the signs. BIOSKINCLEAR does what it takes to heal acne pimples, pigmentation and scars

• Takes care of the immoderate inflammatory reaction — generated by even the smallest lesion in the sebum canals — by helping the protective methods of the innate immune system of the skin, directly, inside the hair follicles and right in the site of skin lesions.

• Provides cellular messengers that communicate to your body that it is being looked after and can moderate an otherwise extreme inflammatory reaction that may finish eliminating healthy skin cells and not just the bacteria and sebum that has become a foreign matter.

• Fights bacterial infection signalling your system to augment the release of the skin's own innate antimicrobial peptides, which are in charge of defending your system and make the skin an unwelcome site for bacteria, microbes and parasites and can’t possibly create any bacterial resistance whatsoever.

• Unplugs blocked pores with gentle enzymes that dissolve or "digest" the plugs, and without peeling and no dryness. They actually do just the opposite, while moisturizing our skin in all ways and triggering healthy skin regeneration, the removal of scars and abnormal pigmentation and the release of amino-acids that rebuild damaged skin tissues quickly. It also alleviates the secondary reactions of Isotretinoin drugs (Accutane® and other brand names) by strengthenning the skin.

• Scavenges free radicals

What makes it so good in counteracting the triggers of acne?

The facts show acne is an inflammatory skin condition which main characteristic are superficial skin eruptions. And those can or can’t become infected with the acne bacteria living within the hair follicles.

Did you hear that Propionibacteria acnes, the bacteria that is the main responsible for acne infections lives in symbiosis with our body, feeding on our damaged cells, collaborating with the sebaceous glands to transform them into sebum, and metabolizing components of sebum into fatty acids with antimicrobial characteristics?

The fact is when sebum flows through out the hair follicles to the surface of our skin it aids to lubricate our skin and defends our skin as it contains lactic acid and fatty acids. Both acids avoid the development of some pathogenic bacteria and fungi, which always prepared to thrive especially in the situations when our immune system becomes weakened.

Fact is that when that sebum does not flow as it should and gets trapped by either clog pores or pinched-off sebum glands — OUCH!— it breaks or destroys part of the lining cells of the sebum tracts. And guess what? Our body readily responds to the Ouch signals. Obviously! It isn’t deaf to them, unlike us that usually have a poor ability to listen to signs of emergency or even to those letting us know of approaching dangers.

Yes, the body answers in very much the very same way it was taught to react during the many years of our evolutionary drift. By sending to the site where the injury is located and insult all its army forces of immune system soldiers (lymphocytes, macrophages, neutrophil) charged with chemical weapons to eliminate the offenders, without consideration even for its own cells that might be in the way and also do get killed. After all this can be seen as a life or death thing!

This is what is meant by “inflammatory reaction”. And, Oh Boy! You might as well bet those soldiers are inflamed!

A model of the pathophysiology of inflammatory acne and skin damage

The figure above shows a complex model of the pathophysiology of inflammatory acne and skin (dermal) damage. In inflammatory acne lesions, NF-κB signal is activated (a transcription factor critical for up-regulation of many proinflammatory cytokine genes). As a consequence, inflammatory cytokine genes (eg. TNF-α and IL-1ß) are activated. These primary cytokines will propagate the inflammatory effects by acting on endothelial cells to make adhesion molecules (eg. ICAM-1) to simplify the recruitment of inflammatory cells into the skin. TNF-α and IL-1ß will also work to stimulate the production of secondary cytokines, such as IL-8, which can help in the movement of the inflammatory cells tending towards the increased amount of these special chemicals. By using their cell surface receptors, TNF-α and IL-1ß not only augment the NF-κB signaling cascade, but also trigger the activation of MAP kinases (mitogen-activated protein kinase) to activate AP-1 mediated gene transcription (another very important transcription factor involved in inflammation). As a side effect of activator protein 1 (AP-1) activation (cJun induction), AP-1-driven matrix metalloproteinases (MMPs), a type of zinc-dependent protease enzymes, are elaborated by resident skin cells. Together with neutrophil collagenase and neutrophil elastase enzymes brought in by (PMNs) polymorphonuclear leukocyte inflammatory cells, they synthesize extracellular matrix proteins like collagen and elastin. After this it comes the matrix synthesis and renovation. This is not a perfect solution. Most of the imperfections have the capacity to leave clinically untraceable deficits in the organization or forming, or both, of the skin matrix. Nevertheless, when they occur to a major extent in time, along with sustained procollagen synthesis, acne scarring becomes clinically visible. American Journal of Pathology. 2005. Inflammation and Extracellular Matrix Degradation Mediated by Activated Transcription Factors nuclear factor-κB and Activator Protein-1 in Inflammatory Acne Lesions in Vivo. Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, US.

Now of course there are factors that "start " hyperactivity of our glands, blocked skin pores, bacterial infection and the like. Stress is the hands-down primary trigger of sebaceous glands hyperactivity that might turn out into acne inflammation. And there are other contributing factors as well. For example, rubbing and squeezing pimples, the pressure pressure or friction (head bands, caps, etc), way of living, birth control pills, cosmetics, climate and food, but stress is the Big Kahuna! Now, "stress" is another tale, and you might afterwards go to our site’s FAQ and find even more in regards to the biology of stress & acne.

Again, you can not blame your own body for producing huge amounts of sebum. The problem is how it reacts to trauma inflicted to the cells that border the sebum canals. When the canals become overcharged with sebum pressing to flow to the surface —where it belongs—, or when they are not able to reach the skin surface because of blocked skin pores and pinched-off sebum glands.

OK! You will attack extremely oily skin and blocked skin pores with an acne treatment product, a certain time, and till your skin is back in balance. And you may as well think of changing some of your nutritional habits to avoid sebum canals pinched-off by the pressure of extreme moisture attracted by toxins expelled from within your dermis by your lymphatic system, as you may learn about by visiting the Acne & Rosacea FAQ and the links there on skin detoxify and about the connection that surround adult acne and dairy products or acne and diet.

Now, what’s with the inflammatory reaction that occurs each time those events happen again as it is guaranteed because of your natural hormonal imbalances? Well that is unless you live in a wonderful, completely stress free world. That perhaps is not a very amusing realm though.

Organizing The Immune Reaction of the Body to Foreign Attackers Can Reduce the Severity of Acne Lesions and Prevent Acne Scars.

Did you understand what is at stake? Modulating the inflammatory response is the recipe for clear skin! Calm down you guys (immune cells), past are the moments when bacteria and other micro-organism were kings. Or is it nothing but wishful thinking? Isn’t it true that we carry on and in the inside of our body three times more bacteria than the the exact number of cells our organism is composed of?

The fact is that our body is ingrained with the memories of all past battles, fought to take care of our body when broken or wounded and does not hear just any discourse made up by the pharmaceutical or cosmetic firms that sell anti acne treatments aiming to control bacteria.

During our evolution, injuries and wounds constituted a serious threat to our organism, not only because of blood loss, but also because of tissue damage or infection from the invasion of foreign bodies like dirt, splinters and bacteria. The adult wound recovery method that evolved to answer to all these threats has two fundamental characteristics: First, there is a rapid and big inflammatory response, with recruitment of activated macrophages, neutrophils and lymphocytes to the injury site; and second, there is a fibrotic "walling-off" response to separate the foreign body, with liquefaction of adjacent tissue that might lead to abscess formation and scarring.

Actually, acne wounds are in this matter similar to any type of skin wound. Our system answers with the same powerful inflammatory knee-jerk to the sebum that is supposed to flow to the surface of the skin but stays clogged inside the hair follicles as if it where a foreign body; or when the production of sebum is too much and the first flow of sebum through the previously empty duct creates shear forces of sufficient magnitude that injure the walls of the sebum canals or the pilosebaseous glands.

Inflammation increases when acne bacteria (Propionibacterium acnes) and other deliriously happy bacteria always present on the surface of the skin (Staphylococcus aureus, Staph. epidermidis, diphtheroids, streptococci, Candida, etc) start to proliferate uncontrollably in punctured or broken skin. The problem is magnified if right there the deliciously rich feeding fatty sebum is plenty.

"An abscess and its subsequent scar is not an evolutionarily optimized end point for today's injuries, Dr. Mark Ferguson, D.D.S., Ph.D., professor in the faculty of life sciences at the University of Manchester, England, says. The abscess and scarring response, with its massive inflammatory overdrive, is optimized for a very different type of skin lesion than those occurring nowadays where hygiene and clean faces and bodies rule. The abscess and scar is induced by this inappropriate inflammatory response..."

Lesions that hurt the cells lining the sebum canals, arising due to a sudden increase in the flow of sebum or pinched-off sebum glands, occur in otherwise clean skin without dirt or contamination by foreign bodies. These wounds should therefore be the best candidates for healing without problems using a regenerative wound healing method rather than a scarring method. The consequence should be marked by scar less recovery.

The healing time within the hair follicles should be very similar to what our system accomplishes for fetal injuries that heal in a fast way by regenerating cells and leaving absolutely no trace behind.

Something is missing in all the other treatments out there. Something that would tell your body that it is being taken care of in a proper way and does not need to overly react with its inflammatory battalion. Not just the innate or artificial ingredients that fight against the symptoms, when it is already too late: acne bacteria gone uncontrollable, occlusion of the ducts (microcomedones) and then enlarged comedones that become inflammatory wounds.

This is a vicious cycle causing repeated and/or increased obstruction of the outflow of the sebum, which in turn leads to even more pressure, more inflammation and continue or progressive infection.

This continued obstruction, with or without infection, leads to the forming of cysts. Infection of a cyst produces the formation of an abscess which can lead to local tissue destruction. If this damage of tissue has involved the connective tissue elements of the skin or subcutaneous tissues to a satisfactory level, healing is frequently accompanied and/or followed by the formation of a scar.

Acne scars can range from small to large and severely disfiguring conditions which are eternal consequences of acne. While the mechanism by which acne first appears and lasts for an indefinite period of time might and frequently does stops as a result treatment or spontaneously but the scars persist for life unless they are eliminated.

A Surprising Solution from Life's Genious

Fortunately we’ve found, by chance and sharp analysis, an even better model. One adapted as a different evolutionary immune reaction and cell renewal system, by a group of invertebrates (spineless animals). It is recognized as the innate immune system, also playing a part as the first line of defense and quick maximal reaction against infections and foreign matters in the human body, and opposite to the delayed structured reaction of our acquired (or adaptive) immune system.

Our innate immune system is made of the cells and mechanisms that protect the host from infection of other bodies, in a non-specific manner. This indicates that the cells of the innate system identify, and respond to germs in a generic way, but unlike the adaptive immune system, it does not confer long-lasting or protective defensive immunity to the host.

Although apparently less complex compared to the immune systems of all vertebrates, invertebrate immunity is way older in terms of its evolution, and likely served as the progenitor to sophisticated vertebrate systems, and also has apparently served this kind of animal well enough to keep their lineage alive for the past several hundred million years.

Invertebrates also answer to lesions and insult from the environment by regenerating damaged cells, and also full organs and their skin, without an immoderate inflammatory reaction and yield quick results and an organized, totally orchestrated, skin repair and remodeling without aberrant scar healing! Yes, this is made by small beings that we, proud humans, many times consider an inferior form of life, in a less evolved evolutionary stage.

Unlike clever herbal, botanical, chemical or cosmeceutical concoctions created in a pharmacy, or by the cosmetic industry, a complex natural substance produced by spineless animals of a specific type of land invertebrates is now a full and balanced solution for scar less healing of skin lesions —and its action on acne & rosacea skin conditions may far exceed attempts to copy life's genius in the laboratory.

We explain to you all the facts about the natural skin rejuvenation and regeneration characteristics this substance has —the second half of the solution —, at the INGREDIENTS link in the top menu! But before anything else we need to advise you, for some people look down on such forms of life or viscerally react to them with disgust. Others learn after the fact to be wiser as they can’t be thankful enough for the miracles such natural solutions provide.

You may have seen this little creature in your backyard, if you live in one of those areas of the world with Mediterranean weather and soil conditions. Maybe you even noticed it has a skin with the same structural elements that our skin is made of: collagen, elastin, and all the molecules our skin is made of.

But his way of acting when its skin or some of its organs are damaged and then attacked by micro-organisms is very different than our own strong innate inflammatory reaction. It copiously produces and bubbles and bathes in the ONLY natural secreted substance created by a living mollusk —as a result of its amazing evolutionary drift of millions and millions of years— to moisturize its skin deeply and effectively while at the same time protecting the skin with antimicrobial peptides, antioxidants, and molecules that trigger the orderly regeneration, reconstruction or renovation of whatever cells and structures may be injured.

For our skin, it does, from the outside, the same and even more. It not only strengthen the body's capacity to ingest and destroy infectious particles or dead/dying cells and supports the job of the antimicrobial peptides that our skin produces, such as the ß-defensins, but it also surprisingly restores balance to skin affected by innate hormonal conditions, such as acne and rosacea, and not only to skin affected by lesions and injuries arising from accidents, hazards or environmental contamination, damaging UV radiation, parasites, bacteria, fungus, virus or chemicals.

The molecules in this natural substance tell the body that it’s being taken care of and needs NOT respond to bothering agents with uncontrolled inflammatory reactions, for it’s being supplied with the right proteins, enzymes and nutrients necessary to easily control bacteria and to trigger scar less healing. Thus it is in a completely different way compared to our evolutionary drive has conditioned us humans to over-respond to those factors, from within, as the most effective means to thrive in an environment that was ruled by infectious bacteria.

For this was homo sapiens reality during hundreds and hundreds of years till society learned about hygiene and actual science discovered antibiotics —which have an anti-inflammatory effect that is now assumed to be a far more important effect for people who suffer from severe acne and rosacea than it is the anti-biotic effect (which means anti-life) that eliminates bacteria.

Topical application of this substance fabricated by this little mollusk, very soon right after the first signs of acne pimples prevents the cells from initiating the signaling cascade that brings about acne inflammatory reactions and healing through the scarring pathway. It seems to accomplish this by altering the local environment in a method that helps the scar less healing pathway.

The biological substance works for its maker in such an irreducible complex way that it can be a task to try to put in words how specifically it coordinates the response of the immune cells, especially the macrophages, which are the oldest and most consistently kept immunologic competent cells known. When these cells are activated, they trigger a cascade of events which enhances immunity. All the functions, including phagocytosis (ability to engulf foreign cells, materials and particles), liberation of certain cytokines (intercellular "messages") and the processing of antigens are improved.

From the start of our efforts to sell a product for skin care made from this natural substance, our very own clients where telling us that it not only relieve the consequences of acne breakouts & rosacea, it can also prevent acne breakouts and rosacea when it’s used two times a day on clean skin as a routine skin care regimen to keep skin clear of blemishes. It helps as well with the repair of daily and accumulated damage created by exposure to UV radiation and by free radical oxidation.

This gel has also been very good for the treatment of rosacea signs, helping to stop and avoid inflammation, restore the capacity of skin to intricately orchestrate its renewal in an organized way, strengthening blood vessels, cell walls and circulation; while helping to avoid further rosacea outbreaks.

Natural Acne Gel, Rosacea Remedy & Scar Healing

This gel is an oil free product and is a natural remedy for acne, rosacea, and scar healing with moisturizing seaweed extracts. Best for people with very oily skin conditions. All our products are safe for children, moms-to-be and breast fedding mothers.

Made in the USA. One Month's supply 50 grams = 1.76 oz

50 Grams in One Airless Pump Bottle: $49

Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply

Discount Price Two Bottles: $39.20 each, at checkout within our secure shopping cart.