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Copper Peptides in BIOSKINCARE & BIOCUTIS products
In the snail's body tissues, glycosaminoglycans (GAGs) are primarily located inside granules and in the shell, and are secreted onto the surface as a mucous material. Snail glycosaminoglycan tightly binds divalent copper cations (Cu 2+) and form copper peptides, with have skin regeneration properties. The concentration of copper in the snail secretions is notable, but copper peptides have been shown to be active in nanomolar amounts.
Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5):H1821-7.
Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing.
Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery .
Aging reversal of skin
The greatest interest in copper peptides is in the area of reversing the effects of human ageing and ultraviolet damage on human skin. During ageing, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number.
A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
Moisturize, Protect, Repair and Renew Your Skin with BIOSKINCARE CREAM
A deeply moisturizing natural skin care cream that triggers the regeneration of damaged cells while preventing and removing scars, keratosis, psoriasis scales and all types of skin blemishes and replenishes the lipid barrier of the skin.
Made in the USA. One Month's supply 50 grams = 1.76 oz
50 Gram Bottle: $59.98
Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply
Discount Price Two Bottles: $47.98 each, at checkout within our secure shopping cart.
Natural Acne Gel, Rosacea Remedy & Scar Healing
This gel is an oil free product and is a natural remedy for acne, rosacea, and scar healing with moisturizing seaweed extracts. Best for people with very oily skin conditions. All our products are safe for children, moms-to-be and breast fedding mothers.
Made in the USA. One Month's supply 50 grams = 1.76 oz
50 Grams in One Airless Pump Bottle: $49
Save at least 20% off price & save on domestic or world wide shipping costs
when you order more than one month's supply
Discount Price Two Bottles: $39.20 each, at checkout within our secure shopping cart.
Ultra Exfoliate Your Skin with BIOSKINEXFOL
Home microdermabrasion cream. Results are not only immediate, but compound over time and do not trigger inflamm-aging of delicate skin tissues. Best for aged skin, actinic keratosis scales, raised hypertrophic scar treatment and rough stretch marks or ice-pick and old acne scars. Not for keloids. Contains the same natural ingredients in BIOSKINCARE™ but infused with micro-crystals so that you may rub it, with your finger tips to remove old, hard and tough scars or stretch marks by a physical breakdown of the scar tissues. Enzymes in the cream liquefy damaged proteins more thoroughly and helps to release amino-acids that aid to rebuild damaged tissues quickly.
Made in the USA. Two to Three Month's supply 120 grams = 4.23 oz
120 Gram Bottle: $79
Get Rid Of Sun & Age Spots While Revitalizing and Protecting the Skin From The Effects of Free Radicals
A deeply moisturizing natural skin care cream that replenishes the lipid barrier of the skin and triggers the repair of cells damaged by UV radiation and Free Radicals. Also gets rid of brown, sun and age spots, actinic keratosis scales and all types of skin blemishes. The same ingredients in BIOSKINCARE with an added natural substance that reduces melanin hyperpigmentation and a biomimetic peptide that inhibits the accumulation of melanin pigments.
One Month's Supply 1.76 oz., 50 Gram Bottle: $69.98
Prevent & Repair New Stretch Marks, Firm Breasts and Reduce Cellulite with BIO STRETCH MARK CREAM
To prevent pregnancy stretch marks, strengthen fragile skin, firm sagging breasts and body areas and reduce cellulite. It also works for newly formed stretch marks and scars, while BIOSKINEXFOL works best for old, rough and raised marks. This is similar to the cream in BIOSKINCARE, in a more economical container, with 6 oz. but for use only on the body, not on the face, because it contains a higher concentration of our natural biological complex which results in an invisible film that retains in moisture by occluding the area where it is applied but may feel a little tacky on the face.
Made in the USA. Three Month's supply 180 grams = 6 oz
180 Grams In Tottle: $119.00
January 06, 2009
BIOCUTIS skin treatment products
BIOSKINCARE™
A deeply moisturizing natural skin care cream that triggers the regeneration of damaged cells and replenishes the lipid barrier of the skin while preventing and removing scars from accidental injuries and post surgery; stretch marks; hypertrophic and keloid scars; keratois pilaris, actinic keratosis, dermatitis, psoriasis scales and all types of skin blemishes. 50 gram (1.76 oz) jar = $59.98 and for two or more 20% off
BIO SKIN REJUVENATION™
Same cream base and enzymes as in BIOSKINCARE to "digest" or dissolve blemishes, speed skin turnover, moisturize and tighten skin, and two added ingredients: a natural pigment reducer and a human growth factor peptide, derived from the melanocyte-stimulating-hormone that blocks melanin synthesis, and inhibits the formation of unwanted pigmentation, allowing control over skin tone and brown spots. Leaves skin bright and refreshed! 50 gram (1.76 oz) jar = $69.98.
BIOSKINEXFOL™
A home micro-dermabrasion cream with high quality micro-crystals, the same that professionals use to breakdown and polish away hard, rough and old scar tissues. It allows for a deeper penetration of our all natural skin moisturizing and regeneration complex that is combined with the crystals in the microdermabrasion cream. 120 gram (4 oz) jar = $79
BIO STRETCH MARK CREAM™
Helps to prevent pregnancy stretch marks, strengthen fragile skin, firm sagging breasts and body areas and reduce cellulite. It also works for newly formed stretch marks and scars, while BIOSKINEXFOL is recommended for old, rough and raised marks. This product is similar to BIOSKINCARE, although in a more economic container, with 6 oz. For use preferably on the body, not on the face, for it contains a higher concentration of our natural biological complex which results in an invisible film that retains in moisture by occluding the area where it is applied and could feel a little tacky on the face depending on how oily is your facial skin. 6 oz (180g) tottle = $119.00
BIOSKINCLEAR™
An oil free gel for acne, rosacea and facial scars, for people with very oily skin complexion. The product is based on the biological glycoconjugates compound produced to function as a powerful immune modulator and skin regeneration trigger by the snail of the species Helix Aspersa Müller. Removes dead cells and the debris and/or keratin plugs that block sebum canals. And dissolves scar tissues by enzymatic hydrolysis, without peeling. Promotes the secretion of antimicrobials on the skin surface that keep microbes at bay and control acne bacteria. Boosts the production of glycosaminoglycans, the water holging molecules in healthy skin, thus truly moisturizing the skin from within. Signals the immune system that the body is being taken care of and can moderate an otherwise severe inflammatory reaction that may end in the destruction of healthy skin cells together with bacteria and sebum that has turned into a foreign matter. 50 gram (1.76 oz) airless pump bottle $49 and 20% off for two or more.
BIOSKINBALM
Rescues your skin from the ravages of eczema, dermatitis, psoriasis, very dry skin, skin rashes, rosacea symptoms and more. Boosts the production of the water holding molecules present in the dermis and retains water, induces the proliferation of antimicrobial peptides that keep skin infections at bay, moderates inflammation, relieves rashes, dryness and redness, unclogs pores while replenishing the lipid barrier of the skin to block the penetration of allergens. Stimulates the regeneration of damaged cells, prevents and removes scars, actinic keratosis, psoriasis scales and removes all types of skin blemishes.50 gram bottle $59.98.
Keywords: copper peptides, tissue protection, repair properties , skin regeneration properties
